Search for: All records

Intersection movement assist (IMA) is a connected vehicle (CV) application to improve vehicle safety. GPS spoofing attack is one major threat to the IMA application since inaccurate localization results may generate fake warnings that increase rear-end crashes, or cancel real warnings that may lead to angle or swipe crashes. In this work, we first develop a GPS spoofing attack model to trigger the IMA warning of entry vehicles at a roundabout driving scenario. The attack model can generate realistic trajectories while achieving the attack goal. To defend against such attacks, we further design a one-class classifier to distinguish the normal vehicle trajectories from the trajectories under attack. The proposed model is validated with a real-world data set collected from Ann Arbor, Michigan. Results show that although the attack model triggers the IMA warning in a short time (i.e., in a few seconds), the detection model can still identify the abnormal trajectories before the attack succeeds with low false positive and false negative rates. 

Abstract Atrophic fracture nonunion poses a significant clinical problem with limited therapeutic interventions. In this study, we developed a unique nonunion model with high clinical relevance using serum transfer-induced rheumatoid arthritis (RA). Arthritic mice displayed fracture nonunion with the absence of fracture callus, diminished angiogenesis and fibrotic scar tissue formation leading to the failure of biomechanical properties, representing the major manifestations of atrophic nonunion in the clinic. Mechanistically, we demonstrated that the angiogenesis defect observed in RA mice was due to the downregulation of SPP1 and CXCL12 in chondrocytes, as evidenced by the restoration of angiogenesis upon SPP1 and CXCL12 treatment in vitro. In this regard, we developed a biodegradable scaffold loaded with SPP1 and CXCL12, which displayed a beneficial effect on angiogenesis and fracture repair in mice despite the presence of inflammation. Hence, these findings strongly suggest that the sustained release of SPP1 and CXCL12 represents an effective therapeutic approach to treat impaired angiogenesis and fracture nonunion under inflammatory conditions. 

Connected and automated vehicles (CAVs) extend urban traffic control from temporal to spatiotemporal by enabling the control of CAV trajectories. Most of the existing studies on CAV trajectory planning only consider longitudinal behaviors (i.e., in-lane driving), or assume that the lane changing can be done instantaneously. The resultant CAV trajectories are not realistic and cannot be executed at the vehicle level. The aim of this paper is to propose a full trajectory planning model that considers both in-lane driving and lane changing maneuvers. The trajectory generation problem is modeled as an optimization problem and the cost function considers multiple driving features including safety, efficiency, and comfort. Ten features are selected in the cost function to capture both in-lane driving and lane changing behaviors. One major challenge in generating a trajectory that reflects certain driving policies is to balance the weights of different features in the cost function. To address this challenge, it is proposed to optimize the weights of the cost function by imitation learning. Maximum entropy inverse reinforcement learning is applied to obtain the optimal weight for each feature and then CAV trajectories are generated with the learned weights. Experiments using the Next Generation Simulation (NGSIM) dataset show that the generated trajectory is very close to the original trajectory with regard to the Euclidean distance displacement, with a mean average error of less than 1 m. Meanwhile, the generated trajectories can maintain safety gaps with surrounding vehicles and have comparable fuel consumption. 

Abstract The 2015 Paris Agreement proposed targets to limit global-mean surface temperature (GMST) rise well below 2°C relative to preindustrial level by 2100, requiring a cease in the radiative forcing (RF) increase in the near future. In response to changing RF, the deep ocean responds slowly (ocean slow response), in contrast to the fast ocean mixed layer adjustment. The role of the ocean slow response under low warming targets is investigated using representative concentration pathway (RCP) 2.6 simulations from phase 5 of the Coupled Model Intercomparison Project. In RCP2.6, the deep ocean continues to warm while RF decreases after reaching a peak. The deep ocean warming helps to shape the trajectories of GMST and fuels persistent thermosteric sea level rise. A diagnostic method is used to decompose further changes after the RF peak into a slow warming component under constant peak RF and a cooling component due to the decreasing RF. Specifically, the slow warming component amounts to 0.2°C (0.6°C) by 2100 (2300), raising the hurdle for achieving the low warming targets. When RF declines, the deep ocean warming takes place in all basins but is the most pronounced in the Southern Ocean and Atlantic Ocean where surface heat uptake is the largest. The climatology and change of meridional overturning circulation are both important for the deep ocean warming. To keep the GMST rise at a low level, substantial decrease in RF is required to offset the warming effect from the ocean slow response.